Skip to main content
. Author manuscript; available in PMC: 2019 Jun 26.
Published in final edited form as: Exp Mol Pathol. 2015 Sep 25;99(3):498–505. doi: 10.1016/j.yexmp.2015.09.007

Figure 6. ROC curve analysis to assess the predictive accuracy of RGC-32, FasL, and IL-21 in detecting MS patient relapse.

Figure 6.

The probability (C-statistic, or AUC) of accurately detecting relapse was 90% using RGC-32 (p<0.0001), 88% using FasL (p<0.0001), and 75% using IL-21 (p=0.01). A. In the present cohort, a RGC-32/L13 ratio < 1.27 detected patient relapse with a sensitivity of 71% and a specificity of 95%. B. A FasL/L13 ratio < 52.6 detected patient relapse with a sensitivity of 81% and a specificity of 95%. C. An IL-21/L13 ratio > 16.9 detected patient relapse with a sensitivity of 54% and a specificity of 88%.