Table 1.
Parameter | Swept-source OCT-A | Controls (n = 18) | no-DR (n = 73) | DR (n = 20) | p value∗ |
---|---|---|---|---|---|
VDD | DRI-Triton | 11.2 ± 0.7 | 10.9 ± 0.7 | 10.1 ± 1.0† | 0.0006 |
PLEX Elite | 16.2 ± 1.2 | 14.7 ± 2.8 | 13.3 ± 1.0‡ | 0.002 | |
FAZ area DCP | DRI-Triton | 0.60 ± 0.17 | 0.42 ± 0.17 | 0.60 ± 0.25§ | <0.0001 |
PLEX Elite | 0.78 ± 0.23 | 1.22 ± 0.32¶ | 1.37 ± 0.55¶ | <0.0001 | |
FAZ CI SCP | DRI-Triton | 0.90 ± 0.04 | 0.80 ± 0.109‡ | 0.68 ± 0.19¶ | <0.0001 |
PLEX Elite | 0.83 ± 0.07 | 0.73 ± 0.09 | 0.64 ± 0.21¶ | <0.0001 | |
NoB SCP | DRI-Triton | 3523 ± 341 | 3232 ± 488 | 2801 ± 532 | 0.002 |
PLEX Elite | 6691 ± 343 | 6278 ± 631 | 5813 ± 794¶ | 0.0002 | |
tBL SCP | DRI-Triton | 1.9 × 107 ± 4.5 × 106 | 2.4 × 107 ± 5.7 × 106 | 1.6 × 107 ± 3.5 × 106 | <0.0001 |
PLEX Elite | 4.3 × 107 ± 3.5 × 106 | 3.9 × 107 ± 6.3 × 106 | 3.5 × 107 ± 7.6 × 106∆ | 0.0004 | |
PDS | PLEX Elite | 0.39 ± 0.02 | 0.37 ± 0.04 | 0.34 ± 0.05# | 0.0004 |
PDD | PLEX Elite | 0.44 ± 0.03 | 0.39 ± 0.03¶ | 0.36 ± 0.03¶,∆ | <0.0001 |
VDS | PLEX Elite | 13.2 ± 0.8 | 12.4 ± 1.4 | 11.4 ± 1.8† | 0.001 |
FAZ CI DCP | PLEX Elite | 0.83 ± 0.06 | 0.76 ± 0.10 | 0.69 ± 0.10¶ | <0.0001 |
NoB DCP | PLEX Elite | 8064 ± 944 | 7621 ± 413 | 7128 ± 469¶,‡ | <0.0001 |
tBL DCP | PLEX Elite | 5.8 × 107 ± 8.5 × 106 | 4.9 × 107 ± 5.3 × 106¶ | 4.3 × 107 ± 4.3 × 106¶,|| | <0.0001 |
∗One-way ANOVA analyses: comparison among controls, patients with DM without DR, and patients with DR. Statistical significance was set at p = 0.002 after Bonferroni's correction. Comparison versus controls: †Scheffé's test, p = 0.001; ‡Scheffé's test, p = 0.002; ¶Scheffé's test, p < 0.0001; #Scheffé's test, p = 0.0004. Comparison versus patients with DM without DR: §Scheffé's test, p = 0.002; ∫Scheffé's test, p = 0.0002; ∆Scheffé's test, p < 0.0001; ||Scheffé's test, p = 0.0003. VDD: vessel density at the deep capillary plexus; FAZ: foveal avascular zone; DCP: deep capillary plexus; CI: circularity index; SCP: superficial capillary plexus; NoB: number of branches; tBL: total branches length; PDS: perfusion density at the superficial capillary plexus; PDD: perfusion density at the deep capillary plexus; VDS: vessel density at the superficial capillary plexus.