Table 2.
Significant quantitative macular parameters evaluated on 3 × 3 mm angiocubes.
| Parameter | Swept-source OCT-A | Controls (n = 18) | no-DR (n = 73) | DR (n = 20) | p value∗ |
|---|---|---|---|---|---|
| PDD | DRI-Triton | 0.31 ± 0.02 | 0.32 ± 0.02 | 0.30 ± 0.03§ | 0.0001 |
| PLEX Elite | 0.37 ± 0.05 | 0.36 ± 0.04 | 0.31 ± 0.05#,‡ | 0.0001 | |
| VDD | DRI-Triton | 18.0 ± 1.3 | 18.2 ± 1.2 | 16.8 ± 1.4∫ | 0.0001 |
| PLEX Elite | 13.5 ± 1.9 | 12.8 ± 1.4 | 11.2 ± 1.8†,|| | 0.0001 | |
| FAZ CI DCP | DRI-Triton | 0.75 ± 0.08 | 0.75 ± 0.09 | 0.65±0.19∗∗ | 0.001 |
| PLEX Elite | 0.82 ± 0.05 | 0.67 ± 0.13¶ | 0.64 ± 0.11¶ | <0.0001 | |
| tBL DCP | DRI-Triton | 2.1 × 107 ± 1.9 × 106 | 2.2 × 107 ± 2.1 × 106 | 2.0 × 107 ± 2.4 × 106∫∫ | 0.0007 |
| PLEX Elite | 1.3 × 107 ± 2.3 × 106 | 1.2 × 107 ± 1.7 × 106 | 1.1 × 107 ± 1.8 × 106‡‡ | 0.0007 | |
| FAZ CI SCP | DRI-Triton | 0.72 ± 0.09 | 0.73 ± 0.12 | 0.57±0.20∗∗,∆ | 0.0002 |
| FAZ area DCP | PLEX Elite | 1.06 ± 0.25 | 1.37 ± 0.32 | 1.54 ± 0.54# | 0.0003 |
| NoB DCP | PLEX Elite | 1861 ± 282 | 1765 ± 220 | 1551 ± 216¶¶,§ | 0.0002 |
∗One-way ANOVA analyses: comparison among controls, patients with DM without DR and patients with DR. Statistical significance was set at p = 0.002 after Bonferroni's correction. Comparison versus controls: #Scheffé's test, p = 0.0003; †Scheffé's test, p = 0.0001; ∗∗Scheffé's test, p = 0.002; ¶Scheffé's test, p < 0.0001; ‡‡Scheffé's test, p = 0.001; ¶¶Scheffé's test, p = 0.0004. Comparison versus patients with DM without DR: §Scheffé's test, p = 0.002; ‡Scheffé's test, p = 0.0006; ∫Scheffé's test, p = 0.0001; ||Scheffé's test, p = 0.001; ∫∫Scheffé's test, p = 0.0009; ∆Scheffé's test, p < 0.0001. PDD: perfusion density at the deep capillary plexus; VDD: vessel density at the deep capillary plexus; FAZ: foveal avascular zone; CI: circularity index; DCP: deep capillary plexus; tBL: total branches length; SCP: superficial capillary plexus; NoB: number of branches.