Table 2.
Odd ratios of having traditional cardiovascular risks among hemodialysis patients with insulin resistance.
| High SBP | High DBP | High TC | High LDL-C | Low HDL-C | High TG | IFG | |
|---|---|---|---|---|---|---|---|
| OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | OR (95%CI) | |
| Normal weight | |||||||
| Model 1 | 0.42 (0.20, 0.86)∗ | 0.90 (0.50, 1.63) | 0.80 (0.38, 1.68) | 0.83 (0.49, 1.39) | 1.68 (0.99, 2.86) | 2.79 (1.54, 5.06)∗∗ | 8.22 (4.35, 15.52)∗∗∗ |
| Model 2 | 0.36 (0.17, 0.76)∗∗ | 1.13 (0.60, 2.12) | 0.81 (0.37, 1.75) | 0.78 (0.45, 1.36) | 1.75 (1.01, 3.06)∗ | 3.41 (1.78, 6.53)∗∗∗ | 8.15 (4.14, 16.02)∗∗∗ |
| Overweight/Obese | |||||||
| Model 1 | 1.68 (0.71, 3.97) | 1.05 (0.51, 2.19) | 1.14 (0.52, 2.50) | 0.84 (0.45, 1.58) | 3.65 (1.58, 8.45)∗∗ | 2.90 (1.50, 5.61)∗∗ | 6.06 (2.33, 15.74)∗∗∗ |
| Model 2 | 1.69 (0.66, 4.29) | 0.75 (0.33, 1.68) | 0.99 (0.42, 2.33) | 0.80 (0.41, 1.55) | 4.15 (1.71, 10.06)∗∗ | 3.06 (1.53, 6.13)∗∗ | 10.76 (3.36, 34.5)∗∗∗ |
| Non-diabetes | |||||||
| Model 1 | 0.69 (0.37, 1.31) | 1.15 (0.63, 2.07) | 0.78 (0.39, 1.56) | 0.90 (0.54, 1.51) | 2.38 (1.39, 4.07)∗∗ | 3.40 (1.85, 6.25)∗∗∗ | 10.64 (5.78, 19.58)∗∗∗ |
| Model 2 | 0.61 (0.31, 1.18) | 1.21 (0.64, 2.30) | 0.64 (0.31, 1.35) | 0.76 (0.44, 1.33) | 2.14 (1.23, 3.75)∗∗ | 3.22 (1.69, 6.12)∗∗∗ | 12.54 (6.39, 24.63)∗∗∗ |
| Diabetes | |||||||
| Model 1 | 1.49 (0.54, 4.15) | 0.93 (0.45, 1.93) | 1.00 (0.43, 2.32) | 0.77 (0.41, 1.45) | 2.40 (1.07, 5.38)∗ | 3.75 (1.91, 7.37)∗∗∗ | |
| Model 2 | 2.11 (0.70, 6.31) | 0.94 (0.43, 2.05) | 1.16 (0.44, 3.05) | 0.78 (0.40, 1.54) | 3.07 (1.28, 7.33)∗ | 4.29 (2.05, 8.98)∗∗∗ | |
| Overall | |||||||
| Model 1 | 0.80 (0.47, 1.37) | 1.00 (0.63, 1.58) | 0.80 (0.47, 1.37) | 0.72 (0.48, 1.07) | 2.65 (1.71, 4.11)∗∗∗ | 3.67 (2.39, 5.66)∗∗∗ | 8.14 (4.77, 13.89)∗∗∗ |
| Model 2 | 0.76 (0.43, 1.32) | 1.11 (0.68, 1.83) | 0.75 (0.42, 1.32) | 0.63 (0.41, 0.96)∗ | 2.53 (1.59, 4.01)∗∗∗ | 3.58 (2.25, 5.69)∗∗∗ | 7.99 (4.50, 14.18)∗∗∗ |
Significant level at ∗ p < 0.05, ∗∗ p < 0.01, and ∗∗∗ p < 0.001.
Model 1: elevated HOMA-IR and traditional CVD risk factors.
Model 2: adjusted for age, gender, hemodialysis vintage, Charlson comorbidity index, physical activity, and body mass index (for nondiabetes, diabetes, and overall sample).
SBP, systolic blood pressure; DBP, diastolic blood pressure; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TG, triglyceride; IFG, impaired fasting glucose.