Table 1.
Baseline Characteristics
| HUNT2 (n = 590) | HUNT3 (n = 194) | EGCUT (n = 227) | FR (n = 272) | RS (n = 173) | ALL (n = 1456) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | Statistics | Cases | Controls | Statistics | Cases | Controls | Statistics | Cases | Controls | Statistics | Cases | Controls | Statistics | Cases | Controls | Statistics | |
| Total, n (%) | 158 (26.8%) | 432 (73.2%) | 64 (33%) | 130 (67%) | 76 (33.5%) | 151 (66.5%) | 57 (21%) | 215 (79%) | 89 (51.4%) | 84 (48.6%) | 444 (30.5%) | 1012 (69.5%) | ||||||
| Female, n (%) | 80 (50.6%) | 220 (50.9%) | P = 0.95 | 37 (57.8%) | 76 (58.5%) | P = 0.93 | 44 (57.9%) | 88 (58.3%) | P = 0.96 | 22 (38.6%) | 82 (38.1%) | P = 0.95 | 54 (60.7%) | 45 (53.6%) | P = 0.35 | 237 (53.4%) | 511 (50.5%) | P = 0.31 |
| Age, y, mean (SD) | 66.8 ± 11.1 | 64.8 ± 11.2 | P = 0.065 | 69.5 ± 9.5 | 69.5 ± 9.3 | P = 0.97 | 63.4 ± 10.6 | 63.3 ± 10.5 | P = 0.94 | 59.7 ± 8.8 | 59.8 ± 8.9 | P = 0.96 | 71.6 ± 8.5 | 70.9 ± 9.2 | P = 0.62 | 66.6 ± 10.7 | 64.6 ± 10.8 | P = 0.001a |
| BMI, kg/m2, mean (SD) | 27.3 ± 4.1 | 26.9 ± 3.7 | P = 0.28 | 28.3 ± 3.6 | 27 ± 4.2 | P = 0.025a | 29.1 ± 5.8 | 28.5 ± 5.4 | P = 0.40 | 27.2 ± 3.9 | 27.7 ± 4.3 | P = 0.45 | 27.4 ± 4.1 | 27.3 ± 4.1 | P = 0.89 | 27.8 ± 4.4 | 27.3 ± 4.3 | P = 0.078 |
| DM, n (%) | 11 (7%) | 18 (4.2%) | P = 0.16 | 10 (15.6%) | 8 (6.2%) | P = 0.034a | 33 (43.4%) | 32 (21.2%) | P = 0.00059a | 6 (10.5%) | 21 (9.8%) | P = 0.86 | 12 (13.5%) | 2 (2.4%) | P = 0.0074a | 72 (16.2%) | 81 (8%) | P = 2.77 × 10−6a |
| Smoking, n (%) | 0 = 49 (31%) | 0 = 187 (43.3%) | P = 0.00041a | 0 = 22 (34.4%) | 0 = 58 (44.6%) | P = 0.00077a | 0 = 38 (50%) | 0 = 100 (66.2%) | P = 0.044a | 0 = 21 (36.8%) | 0 = 106 (49.3%) | P = 0.043a | 0 = 22 (24.7%) | 0 = 20 (23.8%) | P = 0.021a | 0 = 152 (34.2%) | 0 = 471 (46.5%) | P = 8.12 × 10−9a |
| 1 = 48 (30.4%) | 1 = 140 (32.4%) | 1 = 19 (29.7%) | 1 = 55 (42.3%) | 1 = 18 (23.7%) | 1 = 20 (13.2%) | 1 = 14 (24.6%) | 1 = 66 (30.7%) | 1 = 37 (41.6%) | 1 = 50 (59.5%) | 1 = 136 (30.6%) | 1 = 331 (32.7%) | |||||||
| 2 = 59 (37.3%) | 2 = 93 (21.5%) | 2 = 20 (31.3%) | 2 = 13 (10%) | 2 = 20 (26.3%) | 2 = 31 (20.5%) | 2 = 19 (33.3%) | 2 = 41 (19.1%) | 2 = 27 (30.3%) | 2 = 12 (14.3%) | 2 = 145 (32.7%) | 2 = 190 (18.8%) | |||||||
| NA = 2 (1.3%) | NA = 12 (2.8%) | NA = 3 (4.7%) | NA = 4 (3.1%) | NA = 0 (0%) | NA = 0 (0%) | NA = 3 (5.3%) | NA = 2 (0.9%) | NA = 3 (3.4%) | NA = 2 (2.4%) | NA = 11 (2.5%) | NA = 20 (2%) | |||||||
| Fasted, n (%) | 0 = 134 (84.9%) | 0 = 363 (84%) | P = 0.95 | 0 = 46 (71.9%) | 0 = 97 (74.6%) | P = 0.32 | 0 = 35 (46.1%) | 0 = 97 (64.2%) | P = 0.87 | 0 = 4 (7%) | 0 = 4 (1.9%) | P = 0.052 | 0 = 26 (29.2%) | 0 = 21 (25%) | P = 0.50 | 0 = 245 (55.2%) | 0 = 582 (57.5%) | P = 1.49 × 10−5a |
| 0 = ≤4 h, 1 = 4 h to 8 h | 1 = 19 (12%) | 1 = 56 (13%) | 1 = 9 (14.1%) | 1 = 18 (13.8%) | 1 = 7 (9.2%) | 1 = 24 (15.9%) | 1 = 38 (66.7%) | 1 = 171 (79.5%) | 1 = 1 (1.1%) | 1 = 0 (0%) | 1 = 74 (16.7%) | 1 = 269 (26.6%) | ||||||
| 2 = >8 h | 2 = 3 (1.9%) | 2 = 9 (2.1%) | 2 = 6 (9.4%) | 2 = 5 (3.8%) | 2 = 6 (7.9%) | 2 = 15 (9.9%) | 2 = 14 (24.6%) | 2 = 40 (18.6%) | 2 = 56 (62.9%) | 2 = 57 (67.8%) | 2 = 85 (19.1%) | 2 = 126 (12.5%) | ||||||
| NA = 2 (1.3%) | NA = 4 (0.9%) | NA= 3 (4.7%) | NA = 10 (7.7%) | NA = 28 (36.8%) | NA = 15 (9.9%) | NA = 1 (1.8%) | NA = 0 (0%) | NA = 6 (6.7%) | NA = 6 (7.1%) | NA = 40 (9%) | NA = 35 (3.5%) | |||||||
Values are number counts (percentages) or mean ± SD. P values are from χ2 test (categorical variables) or Student t test (continuous variables) comparing cases and controls.
Abbreviation: NA, not available.
a
P < 0.05.