. 2019 Mar 10;11(2):176–186. doi: 10.1111/os.12439

Table 1.

Characteristics of included studies

No.	Included studies	Treatment group 1			Treatment group 2			Study design	Treatment course (months)
No.	Included studies	Treatment	Sample size (male/female)	Age (years)	Treatment	Sample size (Male/Female)	Age (years)	Study design	Treatment course (months)
1	Liu et al. (2016)20	Jintiange + BP	58 (22/36)	71 ± 5^†	BP	58 (24/34)	70 ± 6^†	RCT	12
2	Xia & Tang (2013)10	Jintiange + calcium	110 (61/49)		Calcium +/VD	120 (62/58)		RCT	12
3	Wang et al. (2014)35	Jintiange + BP + calcium	43 (19/24)	64 ± 6 ^†	Calcium +/VD	43 (18/25)	64 ± 6 ^†	RCT	12
4	Xia & Wang (2015)31	Jintiange + calcium	35 (0/35)		Calcium +/VD	35 (0/35)		RCT	16
5	Peng et al. (2018)38	Jintiange + BP	55 (0/55)		BP	55 (0/55)		Non‐RCT	12
6	Xu et al. (2017)21	Jintiange + Estrogen	50 (0/50)	61.47 ± 7.38 ^†	Estrogen	50 (0/50)	61.98 ± 6.92 ^†	RCT	12
7	Du & Shao (2014)34	Jintiange capsule	78	65 (50–73)^‡	BP + calcium	78	64 (48–72) ^‡	RCT	6
8	Song et al. (2016)17	Jintiange + atorvastatin	50 (21/29)	65 (51–74) ^§	Jintiange capsule	50	64 (49–73) ^§	RCT	6
9	Yu et al. (2016)16	Jintiange + atorvastatin	30 (12/18)	66 (53–75) ^‡	Jintiange capsule	30 (14/16)	64 (51–74) ^‡	RCT	6
10	Xie (2018)24	Jintiange + BP	446 (0/446)		BP	430 (0/430)		Non‐RCT	3
11	Yeerjiang & Wang (2017)33	Jintiange + calcium	100 (53/47)	65.23 ± 11.42 ^†	Calcium +/VD	100 (52,48)	65.74 ± 11.37 ^†	RCT	3
12	Fan et al. (2015)28	Jintiange + calcium	50 (10/40)	62.85 ± 2.25 ^†	Calcium +/VD	50 (11/39)	62.56 ± 2.73 ^†	RCT	3
13	Fu et al. (2016)36	Jintiange + calcium	80 (45/35)	62.7 ± 7.2 ^†	Calcium +/VD	80 (31/49)	60.2 ± 6.0 ^†	RCT	3
14	Huang et al. (2014)₃₂	Jintiange + calcium	84		BP + calcium	82		RCT	3
15	Qin et al. (2016)30	Jintiange capsule	56 (0/56)	62.5 ± 5.0 ^†	Calcium +/VD	56 (0/56)	63.6 ± 2.1 ^†	RCT	3
16	Le (2018)27	Jintiange + BP	56 (0/56)	66.79 ± 3.29 ^†	BP	31 (0/31)	65.68 ± 3.30 ^†	Non‐RCT	6
17	Xi et al. (2016)37	Jintiange + BP	84 (40/44)	63.7 ± 7.1 ^†	BP	83 (41/42)	63.2 ± 6.6 ^†	RCT	6
18	Liu et al. (2018)22	Jintiange + BP	76 (0/75)	59.96 ± 9.24 ^†	BP	75 (0/75)	59.48 ± 9.35 ^†	RCT	6
19	Luo et al. (2015)15	Jintiange + BP	23		Calcium +/VD	23		RCT	6
20	Qi et al. (2017)29	BP + calcium	87 (0/87)	65.3 ± 10.9 ^†	Jintiange + BP + calcium	46 (0/46)	63.9 ± 14.8 ^†	RCT	6
21	Zhang et al. (2014)19	Jintiange + calcitonin	23		Calcitonin	23		RCT	6
22	Dai et al. (2018)26	Jintiange + BP	80 (0/80)	68.26 ± 5.79 ^†	BP	80 (0/80)	67.33 ± 6.35 ^†	RCT	6
23	Gao et al. (2016)3	Jintiange + BP	53		Jintiange capsule	53		RCT	6
24	Luo et al. (2016)14	Jintiange + BP + calcium	56		BP + calcium	54		RCT	6
25	Pan et al. (2016)25	Jintiange + BP	70 (0/70)	67.25 ± 5.43 ^†	BP	70 (0/70)	67.19 ± 5.40 ^†	RCT	6
26	Xu et al. (2015)23	Jintiange + BP + calcium	21	56.3^**	calcium +/VD	21	57.1^**	RCT	12
27	Fu et al. (2017) ^* ^,39	Jintiange + BP + calcium	33	67.3 ± 11.2 ^†	BP + calcium	33	66.9 ± 12.5 ^†	RCT	12
27	Fu et al. (2017) ^* ^,39	Jintiange + BP + calcium	33	67.3 ± 11.2 ^†	calcium +/VD	33	66.6 ± 11.7 ^†	RCT	12
28	Du et al. (2015) ^* ^,34	Jintiange + BP + calcium	34		Jintiange capsule	34		RCT	6
28	Du et al. (2015) ^* ^,34	Jintiange + BP + calcium	34		BP + calcium	34		RCT	6
29	Wang et al. (2014) ^* ^,18	Jintiange + physiotherapy + calcium	32		Jintiange + calcium	32		RCT	3
29	Wang et al. (2014) ^* ^,18	Jintiange + physiotherapy + calcium	32		physiotherapy + calcium	32		RCT	3
30	Hu et al. (2011) ^* ^,40	Jintiange + calcium	36		Jintiange capsule	36		RCT	1
30	Hu et al. (2011) ^* ^,40	Jintiange + calcium	36		Calcium +/VD	36		RCT	1
31	Cai et al. (2015) ^* ^,13	Jintiange + BP	34 (0/34)		Jintiange capsule	32 (0/32)		RCT	6
31	Cai et al. (2015) ^* ^,13	Jintiange + BP	34 (0/34)		BP	32 (0/32)		RCT	6

Jintiange, Jintiange capsule; BP, bisphosphonate; RCT, randomized controlled trail

Three‐arm experiment.

^†

Data are expressed as mean ± SD.

^‡

Mean (minimum‐maximum).

^§

Median (minimum‐maximum).

^**

Mean.