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. 2019 Jun 26;15(6):e1008221. doi: 10.1371/journal.pgen.1008221

Fig 1. Two-by-One model of CI is governed by cifA and cifB genes in the eukaryotic association module of prophage WO in Wolbachia.

Fig 1

The Two-by-One model of CI predicts that D. melanogaster males and females can be engineered to recapitulate both CI and rescue phenotypes in the absence of Wolbachia, thus depending completely on phage genes for successful reproduction. Schematics are not to scale. Insect, sperm, and embryo art were obtained and modified using vecteezy.com. Phage gene schematics modified from [38]. CifA and CifB protein annotation from [40]. Purple indicates eukaryotic association module genes as indicated by [37].