Fig 6. Dectin-1 is important for early neutrophil recruitment.

(A-C) WT and CLR KO mice were injected with 1x10⁵ CFU C. albicans i.p. and inflammatory cells were recovered by peritoneal lavage after 4 h. (A-B) Percentage (A) and total number (B) of recruited neutrophils, Ly6⁺ monocytes and resident macrophages in the peritoneal lavages were measured by flow cytometry. (C) Chemokine and cytokine levels in the lavage fluid were measured by ELISA. (A-C) n = 6–12 mice. Graphs show cumulative data from 3 independent experiments. (1-way ANOVA with Bonferroni’s post-test–Performed on transformed data for total resident macrophages, G-CSF and IL-6; Kruskal-Wallis test with Dunn’s post-test for % Resident macrophages).