TABLE 2.
The crude and adjusted regression coefficient (β) and 95% confidence interval (CI) for final hearing, absolute and relative hearing gain in relation to TBIL and DBIL in full sample
| Crude | Adjusted* | |||
| β (95% CI) | p | β (95% CI) | p | |
| Final hearing | ||||
| TBIL (per 1 μmol/L) | −1.8 (−2.9, −0.6) | 0.003 | −0.3 (−0.9, 0.3) | 0.289 |
| TBIL tertiles | ||||
| T1 | 0 [Reference] | 0 [Reference] | ||
| T2 | −10.8 (−23.4, 1.9) | 0.094 | 2.6 (−4.0, 9.2) | 0.437 |
| T3 | −17.3 (−29.6, −4.9) | 0.006 | −2.6 (−8.5, 3.4) | 0.394 |
| DBIL (per 1 μmol/L) | −1.6 (−6.0, 2.8) | 0.469 | 0.1 (−2.1, 2.3) | 0.896 |
| DBIL tertiles | ||||
| T1 | 0 [Reference] | 0 [Reference] | ||
| T2 | −3.9 (−15.8, 8.1) | 0.525 | −1.4 (−8.4, 5.6) | 0.697 |
| T3 | −3.4 (−17.2, 10.4) | 0.624 | −0.7 (−9.2, 7.7) | 0.868 |
| Absolute hearing gain | ||||
| TBIL (per 1 μmol/L) | 0.2 (−0.5, 0.9) | 0.551 | 0.3 (−0.3, 0.9) | 0.299 |
| TBIL tertiles | ||||
| T1 | 0 [Reference] | 0 [Reference] | ||
| T2 | −1.1 (−7.6, 5.4) | 0.744 | −3.1 (−9.5, 3.2) | 0.337 |
| T3 | 2.3 (−4.8, 9.5) | 0.522 | 2.3 (−3.6, 8.2) | 0.435 |
| DBIL (per 1 μmol/L) | −0.1 (−2.2, 2.0) | 0.925 | −0.2 (−2.4, 2.0) | 0.845 |
| DBIL tertiles | ||||
| T1 | 0 [Reference] | 0 [Reference] | ||
| T2 | 0.0 (−6.5, 6.4) | 0.989 | 0.8 (−5.9, 7.4) | 0.825 |
| T3 | 0.9 (−6.3, 8.0) | 0.808 | 0.3 (−8.0, 8.5) | 0.950 |
| Relative hearing gain | ||||
| TBIL (per 1 μmol/L) | 0.6 (−0.4, 1.5) | 0.261 | 0.3 (−0.5, 1.2) | 0.417 |
| TBIL tertiles | ||||
| T1 | 0 [Reference] | 0 [Reference] | ||
| T2 | 2.9 (−6.9, 12.7) | 0.568 | −1.3 (−10.3, 7.7) | 0.774 |
| T3 | 6.6 (−3.0, 16.3) | 0.178 | 4.0 (−4.3, 12.4) | 0.347 |
| DBIL (per 1 μmol/L) | 0.2 (−2.8, 3.1) | 0.913 | −0.1 (−2.9, 2.8) | 0.962 |
| DBIL tertiles | ||||
| T1 | 0 [Reference] | 0 [Reference] | ||
| T2 | 1.3 (−8.1, 10.6) | 0.788 | 3.5 (−5.8, 12.8) | 0.456 |
| T3 | 1.9 (−8.4, 12.2) | 0.722 | 2.4 (−8.3, 13.1) | 0.657 |
*Adjusted for age, sex, time duration, audiogram, alcohol use, diabetes, preceding infection, baseline hearing level, magnesium, hematocrit, alkaline phosphatase, low-density lipoprotein cholesterol, neutrophil, and platelet.
DBIL indicates direct bilirubin levels; TBIL, total bilirubin levels.