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. 2019 May 23;40(6):728–735. doi: 10.1097/MAO.0000000000002287

TABLE 2.

The crude and adjusted regression coefficient (β) and 95% confidence interval (CI) for final hearing, absolute and relative hearing gain in relation to TBIL and DBIL in full sample

Crude Adjusted*
β (95% CI) p β (95% CI) p
Final hearing
 TBIL (per 1 μmol/L) −1.8 (−2.9, −0.6) 0.003 −0.3 (−0.9, 0.3) 0.289
 TBIL tertiles
  T1 0 [Reference] 0 [Reference]
  T2 −10.8 (−23.4, 1.9) 0.094 2.6 (−4.0, 9.2) 0.437
  T3 −17.3 (−29.6, −4.9) 0.006 −2.6 (−8.5, 3.4) 0.394
 DBIL (per 1 μmol/L) −1.6 (−6.0, 2.8) 0.469 0.1 (−2.1, 2.3) 0.896
 DBIL tertiles
  T1 0 [Reference] 0 [Reference]
  T2 −3.9 (−15.8, 8.1) 0.525 −1.4 (−8.4, 5.6) 0.697
  T3 −3.4 (−17.2, 10.4) 0.624 −0.7 (−9.2, 7.7) 0.868
Absolute hearing gain
 TBIL (per 1 μmol/L) 0.2 (−0.5, 0.9) 0.551 0.3 (−0.3, 0.9) 0.299
 TBIL tertiles
  T1 0 [Reference] 0 [Reference]
  T2 −1.1 (−7.6, 5.4) 0.744 −3.1 (−9.5, 3.2) 0.337
  T3 2.3 (−4.8, 9.5) 0.522 2.3 (−3.6, 8.2) 0.435
 DBIL (per 1 μmol/L) −0.1 (−2.2, 2.0) 0.925 −0.2 (−2.4, 2.0) 0.845
 DBIL tertiles
  T1 0 [Reference] 0 [Reference]
  T2 0.0 (−6.5, 6.4) 0.989 0.8 (−5.9, 7.4) 0.825
  T3 0.9 (−6.3, 8.0) 0.808 0.3 (−8.0, 8.5) 0.950
Relative hearing gain
 TBIL (per 1 μmol/L) 0.6 (−0.4, 1.5) 0.261 0.3 (−0.5, 1.2) 0.417
 TBIL tertiles
  T1 0 [Reference] 0 [Reference]
  T2 2.9 (−6.9, 12.7) 0.568 −1.3 (−10.3, 7.7) 0.774
  T3 6.6 (−3.0, 16.3) 0.178 4.0 (−4.3, 12.4) 0.347
 DBIL (per 1 μmol/L) 0.2 (−2.8, 3.1) 0.913 −0.1 (−2.9, 2.8) 0.962
 DBIL tertiles
  T1 0 [Reference] 0 [Reference]
  T2 1.3 (−8.1, 10.6) 0.788 3.5 (−5.8, 12.8) 0.456
  T3 1.9 (−8.4, 12.2) 0.722 2.4 (−8.3, 13.1) 0.657

*Adjusted for age, sex, time duration, audiogram, alcohol use, diabetes, preceding infection, baseline hearing level, magnesium, hematocrit, alkaline phosphatase, low-density lipoprotein cholesterol, neutrophil, and platelet.

DBIL indicates direct bilirubin levels; TBIL, total bilirubin levels.