Table 1. Body weight, weight gain, organ weight and sperm motility after TCE exposure as a function of route of exposure and recovery.
TCE toxicity measured via body weight, weight gain, testis weight, epididymis weight and sperm motility for 0- 6- and 12- week recovery time points and water and gavage TCE exposure routes. Weights of left and right organs are combined (mean ± SEM). Significant measures are bolded and italicized.
Weeks Recovery |
Route | Treatment | Body weight |
Weight gain |
Testis weight |
Epididymis weight |
Motility |
---|---|---|---|---|---|---|---|
0 | water | Control | 309 ±4.91 | 99.5 ±2.67 | 2.97 ±0.05 | 0.94 ± 0.03 | 83.5% ± 2.78 |
TCE | 284 ± 5.65** | 73.1 ± 2.82* | 2.99 ±0.04 | 0.95 ±0.03 | 69.2% ± 5.71† | ||
gavage | Control | 304 ± 3.83 | 90.6 ± 1.73 | 2.99 ±0.04 | 0.92 ± 0.02 | 83.6% ± 3.46 | |
TCE | 270 ± 3.92*** | 65.1 ±4.78** | 3.00 ±0.04 | 0.84 ± 0.02* | 70.9% ± 4.03† | ||
6 | water | Control | 346 ± 7.95 | 132 ±6.46 | 3.19 ±0.05 | 0.99 ±0.03 | 83.3% ± 3.66 |
TCE | 337 ±5.13 | 123 ±3.83 | 3.16 ±0.04 | 1.00 ±0.03 | 75.3% ± 6.88 | ||
gavage | Control | 326 ± 4.88 | 112 ±1.87 | 3.06 ± 0.04 | 0.94 ± 0.02 | 81.2% ±4.75 | |
TCE | 302 ±3.11* | 97 ± 6.52 | 3.13 ±0.03 | 0.95 ± 0.02 | 87.8% ±2.19 | ||
12 | water | Control | 366 ± 8.46 | 146 ±5.52 | 3.18 ±0.05 | 1.02 ±0.02 | 82.5% ± 5.24 |
TCE | 369 ± 9.74 | 144 ±4.58 | 3.27 ±0.05 | 1.03 ±0.03 | 87.6% ± 2.28 | ||
gavage | Control | 367 ± 7.38 | 142 ±3.81 | 3.28 ±0.04 | 1.04 ±0.03 | 81.4% ±5.33 | |
TCE | 346 ± 8.05 | 121.5 ± 4.90** | 3.33 ±0.04 | 1.06 ±0.03 | 77.1% ±5.65 |
p<0.05,
p<0.01,
p<0.001 when exposure groups were tested by ANOVA at each timepoint.
p < 0.01 when tested by t-test between combined “control” and “treated” TCE exposure groups at 0-weeks.