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Schematic representation of the proposed mechanism of circ_0132266 in CLL. circ_0132266 acts as a miR-337-3p sponge to regulate the miR-337-3p/PML pathway. Decreased circ_0132266 in CLL leads to the upregulation of miR-337-3p, which eliminates the suppression effects of PML in CLL progression.
