Table 3.
Adverse Events at least Possibly Related to the Study Drugs (n = 20).
| Adverse Events* | Grade | |||
|---|---|---|---|---|
| 1 | 2 | 3 | 4 | |
| n (%) | ||||
| Hematological toxicity | ||||
| Anemia | 2 (10) | 6 (30) | 9 (45) | 0 |
| Thrombocytopenia | 5 (25) | 2 (10) | 2 (10) | 1 (5) |
| Neutropenia | 0 | 1 (5) | 0 | 0 |
| Non hematological toxicity | ||||
| Weight gain | 3 (15) | 1 (5) | 0 | 0 |
| Shingles | 0 | 3 (15) | 0 | 0 |
| Diarrhea | 1 (5) | 0 | 1 (5) | 0 |
| Fatigue | 0 | 2 (10) | 0 | 0 |
| Nausea | 1 (5) | 0 | 0 | 0 |
| Vomiting | 1 (5) | 0 | 0 | 0 |
| Flatulence | 1 (5) | 0 | 0 | 0 |
| Mouth sores | 1 (5) | 0 | 0 | 0 |
| Pruritus | 1 (5) | 0 | 0 | 0 |
| AST elevation | 1 (5) | 0 | 0 | 0 |
*
Adverse events were graded according to the National Cancer Institute Common Terminology Criteria for Adverse Events (version 4.0)