Skip to main content
. Author manuscript; available in PMC: 2019 Oct 15.
Published in final edited form as: Pediatr Res. 2019 Apr 15;86(1):39–46. doi: 10.1038/s41390-019-0396-6

Figure 1.

Figure 1.

CSE gene deficiency enhances TS -induced AHR and lung inflammation. Groups of CSE KO and WT mice were exposed to side-stream TS or Air (5 h/day, 5 days/week, for two weeks). TS /CSE KO mice have enhanced AHR after MCh challenge (a), influx of total cells (b), macrophages (c), neutrophils (d) and lymphocyte (e) in BAL fluid, increased IL-6, CXCL1, CCL2, and CCL4 (f) compared to TS /WT mice and Air/CSE KO mice, and CSE mRNA levels in the lung (g). Data are expressed as mean ± SEM (n = 4 mice (2 male and 2 female)/group and are representative of three independent experiments). *p<0.05.**p<0.01, ***p<0.001, CSE KO TS vs WT TS, CSE KO TS vs CSE KO Air, CSE KO Air vs WT Air, and WT TS vs WT Air.