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. Author manuscript; available in PMC: 2019 Oct 15.
Published in final edited form as: Pediatr Res. 2019 Apr 15;86(1):39–46. doi: 10.1038/s41390-019-0396-6

Figure 5.

Figure 5.

TS and CSE deficiency enhance BAL cytokines and chemokines following RSV infection. TS - or Air-exposed CSE KO and WT mice were infected with RSV or sham. BAL fluid was collected at different time points after infection to measure cytokines and chemokines by a Bio-Plex array. TS /CSE KO RSV mice had significantly increased levels of cytokines IL-6, IL-12(p40), TNF-α, G-CSF (a) and chemokines CCL2, CCL3, CCL4, CCL5 (b) compared to TS/WT RSV and Air/CSE KO RSV mice. Data are expressed as mean ± SEM (n = 4 mice (2 male and 2 female)/group and are representative of three independent experiments). *p<0.05.**p<0.01, ***p<0.001 CSE KO TS /RSV vs WT TS / RSV, CSE KO TS / RSV vs CSE KO Air/ RSV, CSE KO Air/RSV vs WT Air/RSV, and WT TS / RSV vs WT Air/RSV.