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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: J Acquir Immune Defic Syndr. 2019 Aug 1;81(4):429–438. doi: 10.1097/QAI.0000000000002044

Table 4.

Mixed Effectsa for Secondary Outcomes, N=600

Secondary Outcomes

Hemoglobin Serum Albumin

b 95% CI p-value b 95% CI p-value

Fixed effects
Groupb
 Standard Education (+SE)c
 + Nutrition Education (+NE) 1.99 −0.02, 3.99 .052 −0.37 −1.27, 0.52 .413
 + Nutrition Supplements (+NS) 1.39 −0.61, 3.39 .172 −0.70 −1.59, 0.19 .125
 + Nutrition Education & Supplements (+ NENS) −0.37 −2.42, 1.67 .721 0.38 −0.54, 1.29 .419
Time
 Baselined
 6 month 32.13 30.55, 33.71 <.001 7.69 6.95, 8.42 <.001
 12 months 38.54 36.96, 40.12 <.001 10.37 9.64, 11.11 <.001
 18 months 41.53 39.95, 43.11 <.001 12.19 11.46, 12.93 <.001
Group x Timee
 6-mo x (+NE) 0.50 −1.74, 2.73 .663 1.35 0.31, 2.39 .011
 12-mo x (+NE ) 1.83 −0.40, 4.07 .108 1.11 0.07, 2.15 .037
 18-mo x (+NE) 1.53 −0.71, 3.76 .181 1.12 0.08, 2.16 .035
 6-mo x (+NS) 2.51 0.28, 4.75 .028 2.96 1.92, 4.00 <.001
 12-mo x (+NS) 1.10 −1.13, 3.33 .335 2.37 1.33, 3.41 <.001
 18-mo x (+NS) 0.92 −1.31, 3.15 .420 2.14 1.10, 3.18 <.001
 6-mo x (+NENS)f 6.09  3.86, 8.33 <.001 2.61 1.57, 3.65 <.001
 12-mo x (+NENS)f 7.44  5.21, 9.67 <.001 2.45 1.41, 3.49 <.001
 18-mo x (+NENS)f 6.91  4.68, 9.15 <.001 2.29 1.25, 3.33 <.001
Estimate (95% CI) Estimate (95% CI)
Random effects
 Constant 27.13 (22.92, 32.11) 4.67(3.88, 5.61)
 Residual 48.74 (45.65, 52.04) 10.56 (9.91, 11.30)
Model Statistics Wald X2(24)=15385.32, p < .001 Wald X2(24)=6381.54, p < .001
a

Multilevel model fixed effects: group (ASHA + =reference group), time (baseline=reference group), group X time, % ART adherence and covariates explaining group differences at baseline (age, quality of life, total MET, internalized stigma, social support, food insecurity, education).

b

SE=Program 1 (Standard Education); +NE=Program 2 (Nutrition Education); +NS=Program 3 (Nutrition Supplements); +NENS=Program 4 (Nutrition Education & Nutrition Supplements).

c

SE (Program 1)=reference group.

d

Baseline (Month 0) is the reference group.

e

Baseline and SE (Program 1) are the reference groups.

f

Addative effect are presented, rather than the interaction term.