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. Author manuscript; available in PMC: 2020 Jul 1.
Published in final edited form as: Leuk Lymphoma. 2019 Jan 10;60(7):1740–1748. doi: 10.1080/10428194.2018.1542146

Figure 1. (A) 619 Asparaginase Levels after 86 Induction and Consolidation Doses of Pegaspargase, 2500 IU/m2, in 48 Patients, and (B) 95% Confidence Intervals of 480 Values on Days 1–28.

Figure 1.

Regressions are 2° polynomials were determined with 25 undetectable values (all during days 14–28) assumed to be zero (0). The horizontal, dashed line indicates when, according to the results of this study, asparagine is repleted after asparaginase declines below this level. The polynomial regression is virtually identical if undetectable levels were defined as 0.001 or 0.010 IU/mL