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. 2019 Jun 26;14:217. doi: 10.1186/s11671-019-3032-9

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — The images of confocal microscope and mean fluorescent intensity in RAW 264.7 cells treated with CpG-ODN, CpG-RCA gel (R12), and CpG-MCA gels (R4M4 and R4M8) (100 nM CpG equivalents). CpG-MCA gels and CpG-RCA gel were labeled with Cy5 (red) through adding Cy5-dCTP for their cellular uptake. Cy5-labeled CpG-ODN was used as a control group. a Confocal microscopy images of CpG-RCA gel and CpG-MCA gels by RAW 264.7 cells after incubated for 2 h. b The mean fluorescent intensity of Cy5 in RAW264.7 cells. Results are expressed as the mean ± SD of three independent experiments. ****P < 0.0001