Table 7.
Toxicity profile.
| Study | Toxicity profile (Grade 3/4) |
||||
|---|---|---|---|---|---|
| Anemia, n (%) | Neutropenia, n (%) | Thrombocyto-penia, n (%) | Nausea/Vomiting, n (%) | Diarrhea, n (%) | |
| Van de Putte et al. [13] | 1 (2.6) | 2 (5.1) | 0 (0.0) | 1 (2.6) | – |
| Khaled et al. [17] | 2 (3.4) | 3 (5.2) | 3 (5.2) | 22 (40) | 1 (1.7) |
| Matsubara et al. [20] | 8 (32) | 10 (40) | 10 (40) | – | – |
| Kaneko et al. [22] | 1 (2.4) | 6 (14.3) | 9 (21.4) | 0 (0) | 0 (0) |
| Herchenhorn et al. [23] | 0 (0) | 7 (33.3) | 1 (4.76) | 6 (28.6) | – |
–, not available.