TABLE 4.

Saturation of mutations within and outside binding sites and the UFS element

Bird	Binding sitea	No. of mutations:				Saturation (%) of:		P value	Adjusted P valueb
		Inside	Outside	Per inside site	Per outside site	Inside sites	Outside sites
Crow	UAR	20	94	1.11	0.29	37.04	28.48	0.18	0.70
	DAR I	0	94	0.00	0.29	0.00	28.48	0.009	0.04
	DAR II	5	94	1.00	0.29	33.33	28.48	0.78	1.00
	CYC	0	94	0.00	0.29	0.00	28.48	7.98E−06	0
	All BS	25	94	0.63	0.29	20.83	28.48	0.07	NA
	UFS	0	121	0.00	0.90	0.00	30.10	7.30E−08	NA
Sparrow	UAR	26	130	1.44	0.29	48.15	39.39	0.21	0.84
	DAR I	3	130	0.60	0.29	20.00	39.39	0.19	0.74
	DAR II	7	130	1.40	0.29	46.67	39.39	0.60	1.00
	CYC	0	130	0.00	0.29	0.00	39.39	2.47E−08	0
	All BS	36	130	0.90	0.29	30.00	39.39	0.04	NA
	UFS	0	166	0.00	1.24	0.00	41.29	1.18E−11	NA
Robin	UAR	42	161	2.33	0.29	77.78	48.79	1.60E−05	0
	DAR I	0	161	0.00	0.29	0.00	48.79	6.48E−05	0
	DAR II	12	161	2.40	0.29	80.00	48.79	1.88E−02	0.08
	CYC	1	161	0.08	0.29	2.78	48.79	1.45E−09	0
	All BS	55	161	1.38	0.29	45.83	48.79	0.52	NA
	UFS	1	215	0.06	1.60	2.08	53.48	6.26E−15	NA

^aBS, binding sites.

^bAdjusted with Bonferroni’s correction for multiple comparisons. NA, not applicable.