q |
1.60217733 × 10−19
|
C |
Elementary charge |
K |
1.38065812 × 10−20
|
mJ/K |
Boltzmann’s constant |
T |
273.15 + 22 |
K |
Absolute temperature (corresponds to room temperature at 22 °C) |
|
25.43 |
mV |
Boltzmann’s potential |
RIn |
100 |
MΩ |
Input resistance |
Cm |
130 |
pF |
Membrane capacitance |
υNa
|
70 |
mV |
Reversal potential for Na+
|
υK
|
−90 |
mV |
Reversal potential for K+
|
υL
|
−60 |
mV |
Reversal potential for leak |
āNa
|
13 |
nA |
Maximal amplitude for DmNaυ current |
āK
|
[13, 65] |
nA |
Maximal amplitude for Shab current |
āL
|
0.5 |
nA |
Constant amplitude for leak current |
|
1 |
|
Normalized amplitude for DmNaυ current |
|
[1,5] |
|
Normalized amplitude for Shab current |
|
0.04 |
|
Normalized amplitude for leak current |
|
100 |
nA/nF |
Scaling factor for physiologically relevant dυ/dt
|
υm
|
−28 |
mV |
Half-activation for DmNaυ (Lin et al. 2009; O’Donnell Olson et al. 2008) |
υw
|
−1 |
mV |
Half-activation for Shab (Tsunoda and Salkoff 1995b) |
ηm
|
2 |
|
Gating charge of activation for DmNaυ (estimated from Lin et al. 2009) |
ηw
|
2 |
|
Gating charge of activation for Shab (Tsunoda and Salkoff 1995b) |
τ̄w
|
5 or 10 |
ms |
Maximum time constant for Shab (estimated from Tsunoda and Salkoff 1995b) |
σw
|
0.3 or 0.7 |
|
Symmetry of time constant for Shab (estimated from Tsunoda and Salkoff 1995b) |