Table 4.
Comparison of the antimicrobial activity of tumbo dentifrice against different commercial toothpastes.
| Microorganisms | Groups | Mean ± SD | Min | Max | p ∗ | p | p |
|---|---|---|---|---|---|---|---|
| S. mutans | Pulp | 20.0 ± 2.1 | 17.8 | 25.2 | 0.093 | 0.651++ | p ≤ 0.001† |
| Peel | 16.0 ± 1.5 | 14.6 | 18.6 | 0.008 | |||
| Dento Herbal® | 17.0 ± 0.6 | 16.2 | 17.8 | 0.734 | p ≤ 0.001 | ||
| Colgate Herbal® | 16.9 ± 0.8 | 16.1 | 17.8 | 0.386 | |||
| Kolynos Herbal® | 15.1 ± 0.2 | 14.9 | 15.5 | 0.392 | |||
| Sensodyne® | 11.2 ± 0.8 | 10.0 | 12.0 | 0.191 | |||
| Parodontax® | 30.2 ± 1.5 | 28.9 | 32.5 | 0.194 | |||
|
| |||||||
| E. faecalis | Pulp | 15.5 ± 1.1 | 13.8 | 17.3 | 0.492 | 0.906+ | p ≤ 0.001∗∗ |
| Peel | 15.5 ± 0.4 | 15.0 | 16.5 | 0.647 | |||
| Dento Herbal® | 12.8 ± 0.4 | 12.3 | 13.2 | 0.303 | p ≤ 0.001 | ||
| Colgate Herbal® | 13.9 ± 0.8 | 12.9 | 14.9 | 0.900 | |||
| Kolynos Herbal® | 14.2 ± 0.6 | 13.5 | 14.9 | 0.513 | |||
| Sensodyne® | 10.6 ± 0.3 | 10.2 | 11.0 | 0.408 | |||
| Parodontax® | 15.7 ± 0.2 | 15.5 | 16.1 | 0.649 | |||
|
| |||||||
| Actinomyces | Pulp | 18.3 ± 1 | 17.3 | 20.2 | 0.012 | 0.143++ | p ≤ 0.001† |
| Peel | 18.7 ± 3.3 | 16.3 | 29.1 | 0.000 | |||
| Dento Herbal® | 14.1 ± 0.4 | 13.8 | 14.7 | 0.303 | p ≤ 0.001 | ||
| Colgate Herbal® | 15 ± 0.1 | 14.8 | 15.2 | 0.714 | |||
| Kolynos Herbal® | 13.4 ± 0.1 | 13.2 | 13.6 | 0.000 | |||
| Sensodyne® | 13.2 ± 0.2 | 12.9 | 13.5 | 0.000 | |||
| Parodontax® | 14.1 ± 0.5 | 13.5 | 14.9 | 0.889 | |||
|
| |||||||
| Lactobacillus | Pulp | 20.8 ± 0.6 | 19.8 | 22.1 | 0.623 | p ≤ 0.001+ | p ≤ 0.001∗∗ |
| Peel | 17.6 ± 0.2 | 17.2 | 18.1 | 0.842 | |||
| Dento Herbal® | 17.7 ± 0.6 | 17.0 | 18.3 | 0.443 | p ≤ 0.001 | ||
| Colgate Herbal® | 21.2 ± 0.9 | 20.1 | 22.3 | 0.997 | |||
| Kolynos Herbal® | 22.1 ± 0.8 | 20.9 | 23.0 | 0.696 | |||
| Sensodyne® | 15.5 ± 2.8 | 12.9 | 18.3 | 0.126 | |||
| Parodontax® | 15.2 ± 0.2 | 14.9 | 15.5 | 0.910 | |||
|
| |||||||
| C. albicans | Pulp | 17.4 ± 1.4 | 15.7 | 19.7 | 0.730 | p ≤ 0.001+ | p ≤ 0.001† |
| Peel | 21.1 ± 0.9 | 20.2 | 22.6 | 0.534 | p ≤ 0.001 | ||
| Dento Herbal® | 17.9 ± 0.6 | 17.3 | 18.7 | 0.513 | |||
| Colgate Herbal® | 21.7 ± 0.4 | 21.2 | 22.3 | 0.970 | |||
| Kolynos Herbal® | 20.9 ± 1.5 | 19.9 | 23.2 | 0.025 | |||
| Sensodyne® | 0 | 0 | 0 | — | |||
| Parodontax® | 24.4 ± 0.6 | 23.8 | 25.0 | 0.111 | |||
|
| |||||||
| S. sanguinis | Pulp | 14.9 ± 0.1 | 14.7 | 15.3 | 0.331 | 1.000+ | p ≤ 0.001∗∗ |
| Peel | 15.9 ± 0.4 | 15.3 | 16.6 | 0.447 | |||
| Dento Herbal® | 19.7 ± 0.5 | 19.0 | 20.2 | 0.369 | p ≤ 0.001 | ||
| Colgate Herbal® | 21.1 ± 0.5 | 20.4 | 21.8 | 0.994 | |||
| Kolynos Herbal® | 20.4 ± 1.1 | 19.6 | 22.1 | 0.211 | |||
| Sensodyne® | 0 | 0 | 0 | — | |||
| Parodontax® | 26.1 ± 0.5 | 25.6 | 26.9 | 0.680 | |||
|
| |||||||
| S. oralis | Pulp | 14.5 ± 0.9 | 13.6 | 16.4 | 0.016 | 0.425++ | p ≤ 0.001† |
| Peel | 16.5 ± 0.4 | 15.6 | 17.3 | 0.699 | |||
| Dento Herbal® | 16 ± 0.6 | 15.2 | 16.8 | 0.999 | p ≤ 0.001 | ||
| Colgate Herbal® | 15.6 ± 0.5 | 15.1 | 16.3 | 0.688 | |||
| Kolynos Herbal® | 19.9 ± 0.1 | 19.8 | 20.2 | 0.849 | |||
| Sensodyne® | 0 | 0 | 0 | — | |||
| Parodontax® | 17.7 ± 0.4 | 17.2 | 18.2 | 0.420 | |||
All measurements were made in mm. The concentrations were calculated from the dilutions of the active ingredient; the Sensodyne control group was excluded from any statistical analysis because the antimicrobial activity was not present. ∗Shapiro–Wilk test. +Student t-test. ++Mann–Whitney U test. ∗∗ANOVA test. †Kruskal–Wallis test. Level of significance p < 0.05.