A, Serum total cholesterol changes ± SEM (mmol L−1) after 4‐week treatment (◇: Non significant). B, Correlations between serum total cholesterol change after 4‐week treatment (mmol L−1) and basal serum total cholesterol level (mmol L−1); ●: Nigella sativa, r = −0.71, P = 0.006; ○: Placebo, r = −0.05, P = NS. The slopes of the linear regression lines (full line for Nigella sativa, dashed line for placebo) were significantly different (P = 0.021)