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. 2019 May 9;35(3):506–514. doi: 10.1002/joa3.12184

Table 1.

Baseline demographics and characteristics of 6306 patients in the safety analysis set

Characteristics Overall n = 6306
Women 2592 (41.1)
Age (y) 74.5 ± 10.1 (median 76.0)
<70 1715 (27.2)
≥70 to <75 1189 (18.9)
≥75 to <80 1220 (19.3)
≥80 to <85 1231 (19.5)
≥85 to <90 729 (11.6)
≥90 222 (3.5)
Weight (kg) (n = 5896) 59.6 ± 12.6 (median 59.0)
≤60 3282 (52.0)
>60 2614 (41.5)
Unknown 410 (6.5)
Serum creatinine (mg/dL) (n = 5820) 0.90 ± 0.37
<1.5 5597 (88.8)
≥1.5 223 (3.5)
Unknown 486 (7.7)
Creatinine clearance (mL/min) (n = 5552) 62.2 ± 26.8
<15 4 (0.1)
≥15 to <30 382 (6.1)
≥30 to ≤50 1590 (25.2)
>50 to ≤80 2426 (38.5)
>80 1150 (18.2)
Unknown 754 (12.0)
Past history
Clinically important hemorrhage 221 (3.5)
Congenital or acquired hemorrhagic disease 102 (1.6)
Gastrointestinal ulcer 147 (2.3)
Ischemic stroke and transient ischemic attack 1101 (17.5)
Comorbidity
Hypertension 3855 (61.1)
Heart failure 1921 (30.5)
Diabetes mellitus 1121 (17.8)
Renal disorder 930 (14.7)
Liver disorder 771 (12.2)
Apixaban dosage
5 mg twice daily 3600 (57.1)
2.5 mg twice daily 2694 (42.7)
Othersa 12 (0.2)
Antiplatelet drug useb 1184 (18.8)

Note: Values are mean ± standard deviation or number (%) of patients.

a

See text for details.

b

Antiplatelet drugs that were used during the apixaban dosing period.