Table 2.
Reasons for switching from warfarin to apixaban (n = 2038) | |
Poor INR control | 36.4% |
INR control and adverse events | 0.9% |
Physician's decision | 25.0% |
Patient's preference | 10.3% |
Dietary restrictions | 7.3% |
Others | 10.6% |
Unknown | 9.4% |
INR values at the time of switching from warfarin (n = 760) | |
<1.6 | 61.2% |
1.6 to <2.0 | 8.3% |
2.0 to <2.6 | 2.9% |
2.6 to <3.0 | 2.4% |
≥3.0 | 7.1% |
Unknown | 18.1% |
Reasons for switching from other NOACs (n = 776) | |
Physician's decision | 33.1% |
Efficacy | 15.3% |
Safety concerns | 5.9% |
Blood test results | 5.3% |
Adverse events | 23.3% |
Gastrointestinal symptoms | 10.0% |
Bleeding | 6.1% |
Patient characteristics | 19.8% |
Renal function | 12.9% |
Age | 4.9% |
Patient's preference | 15.7% |
Others | 8.1% |
Abbreviations: INR, international normalized ratio; NOACs, non‐vitamin K oral anticoagulants.