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. 2019 May 24;17:92–101. doi: 10.1016/j.omtn.2019.05.007

Figure 2.

Figure 2

UCA1 Affects the Proliferation and Apoptosis of Ovarian Cancer In Vitro

(A) CCK-8 assay showing UCA1 silencing suppressed the proliferation of A2780-DDP cells in the presence of 4 μg/mL cisplatin. (B) CCK-8 assay showing UCA1 silencing suppressed the proliferation of SKOV-3-DDP cells in the presence of 4 μg/mL cisplatin. (C) CCK-8 assay showing the overexpression of UCA1 promoted the proliferation of A2780 cells in the presence of 4 μg/mL cisplatin. (D) CCK-8 assay showing the overexpression of UCA1 promoted the proliferation of SKOV-3 cells in the presence of 4 μg/mL cisplatin. (E) Flow cytometry analysis of apoptosis in A2780-DDP and SKOV-3-DDP cells transfected with si-Control or si-UCA1 prior to the stimulation of 4 μg/mL cisplatin. (F) Flow cytometry analysis of apoptosis in A2780 and SKOV-3 cells transfected with pcDNAControl or pcDNA-UCA1 prior to the stimulation of 4 μg/mL cisplatin treatment. All tests were performed at least three times. Data were expressed as mean ± SD. **p < 0.01.