Figure 5.
The effect of UCA1 on miR-143 Expression
(A) Silencing of UCA1 increased the expression level of miR-143 in A2780-DDP and SKOV-3-DDP cells. (B) Overexpression of UCA1 decreased the expression level of miR-143 in A2780 and SKOV-3 cells. (C) CCK-8 assay showing miR-143 overexpression markedly inhibits the cell proliferation of A2780-DDP cells in the presence of 4 μg/mL cisplatin. (D) CCK-8 assay showing miR-143 overexpression markedly inhibits the cell proliferation of SKOV-3 cells in the presence of 4 μg/mL cisplatin. (E) CCK-8 assay showing miR-143 inhibitor promoted the proliferation of A2780 cells in the presence of 4 μg/mL cisplatin. (F) CCK-8 assay showing miR-143 inhibitor promoted the proliferation of SKOV-3 cells in the presence of 4 μg/mL cisplatin. All tests were performed at least three times. Data were expressed as mean ± SD. **p < 0.01.