Figure 4.

Adjacent location of arginine fingers and Walker A motifs within gp16 and FtsK ATPases. (A) Comparison of the crystal structure of FtsK and the computed gp16 monomers, which represent a single subunit of a hexameric ATPase, revealing the alignment of the two ATPase subunits even though they are from different species. The arginine finger (red sphere) and the Walker A (blue sphere) overlap when the gp16 and FtsK ATPases are superimposed. (B) Comparison of gp16 and FtsK hexamer models. The green sphere represents Walker domains. The red sphere represents the arginine finger. Based on the proximity of the green and red spheres, the figure reveals that the arginine finger interacts with the adjacent ATPase subunit. Reprinted with permission from ref (110). Copyright 2016 American Society of Microbiology.