Table 4.
Multivariate model regressing DIGEST grade ≥2 dysphagia after RT on clinical factors and RPA-derived dose thresholds.
| Clinical and Dosimetric | Nominal Multivariate Regression Analysis |
|||
|---|---|---|---|---|
| Characteristic | OR (95%CI) | LogWorth | FDR p-value | |
| V61 of GHM ≥ 18.57% | No | 1 | 3.932 | 0.00012* |
| Yes | 32.8 (5.69–335) | |||
| V55 of SPC ≥ 97.46% | No | 1 | 2.773 | 0.0017* |
| Yes | 10.9 (2.7–57.5) | |||
| Treatment Modalities | CCRT Only | 1 | 1.723 | 0.0189* |
| IC+CCRT | 10.64 (2.27–65.72) | |||
| RT alone | 0.79 (0.005–19.02) | |||
| T Stage | 0–2 | 1 | 1.279 | 0.0526 |
| 3–4 | 5.29 (1.16–28.58) | |||
| RT Dose | 1 (1.0002–1.009) | 1.279 | 0.0526 | |
| Baseline DIGEST | 0–1 | 1 | 0.517 | 0.3037 |
| 2–3 | 1 (0.36–42.9) | |||
BIC=101.6, AICc=81.09, AUC=0.909