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. Author manuscript; available in PMC: 2020 Mar 13.
Published in final edited form as: J Am Chem Soc. 2019 Feb 27;141(10):4199–4203. doi: 10.1021/jacs.8b13757

Table 1.

Evaluation of Bis-oxazoline Ligands a,b

graphic file with name nihms-1030605-t0004.jpg
a

Conditions: 1-phenylnon-5-yn-1-one (1a, 0.2 mmol), B(C6F5)3 (10 mol%), 1,2,2,6,6-pentamethylpiperidine (20 mol%), ZnI2 (10 mol%), bis-oxazoline ligand (11 mol%), CH2Cl2 (1.0 mL), under N2, 22 °C, 12 h.

b

Yield was determined by 1H NMR analysis of unpurified reaction mixtures with mesitylene as the internal standard. The er values were determined by HPLC analysis of the purified product.