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. Author manuscript; available in PMC: 2019 Jun 27.
Published in final edited form as: Environ Mol Mutagen. 2012 Apr 17;53(5):358–368. doi: 10.1002/em.21696

Fig. 1.

Fig. 1.

Total DNA adduct levels (A) and cII mutant frequencies (B) in spleen, liver, and kidney of Big Blue rats treated with different doses (0.1, 1.0, and 10.0 mg/kg body weight) of aristolochic acid for 12 weeks. The data represent the mean ± SD of groups of six rats. Spleen data for total DNA adduct levels (C, inner figure of A) and mutant frequencies are from Table II, whereas liver data are from Mei et al [2006] and kidney data are from Chen et al [2006a]. (♦) spleen; (■) liver; and (▲) kidney.