Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 May 14;3(7):1302–1320. doi: 10.1210/js.2019-00053

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Endocrine Society

This article has been published under the terms of the Creative Commons Attribution Non-Commercial, No-Derivatives License (CC BY-NC-ND; https://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Figure 3. — Hippocampal microglia were plated in a 96-well culture plate at 10,000 cells per well and incubated with either (A–C) media (unstimulated) or (D–F) 0.5 μg LPS (stimulated), along with different concentrations of norepinephrine. After 20 hours, supernatants were collected for measurement of IL-1β, IL-6, and TNF-α by ELISA (R&D Systems). Under unstimulated conditions (A–C), norepinephrine resulted in (A) a dose-dependent increase in IL-1β (A). Under LPS-stimulated conditions (D–F), the highest concentration of norepinephrine significantly increased (E) LPS-induced IL-6 release. *P < 0.05 difference from media-treated cells.