Table 1.

Summary Rationale For Neoadjuvant Chemo-RT Versus Adjuvant Chemo For Pancreatic Adenocarcinoma

Comparator Variable	Neoadjuvant Chemo-RT	Up-front Surgery + Adjuvant Chemo	Citations to Support
Rate of Positive Margins	2–20%	16–60%	[16–19]
Incidence of Node Positivity	17–40%	62–80%	[13, 16, 17, 20]
Successful Treatment completion	70–80%	50–60%	[17, 21, 22]
Rates of Local Recurrence	5–15%	19–53%	[13, 17, 18, 23]