Table 2.
Association of patient factors and medical conditions with worsening frailty and function
| Frailty Scaleb | OARS IADL Scaleb | KATZ ADLb,c | ||||
|---|---|---|---|---|---|---|
| OR (95% CI) | P-value | OR (95% CI) | P-value | OR (95% CI) | P-value | |
| Age | 1.05 (1.02, 1.07) | <0.001* | 1.06 (1.03, 1.09) | < 0.001* | 1.08 (1.01, 1.17) | 0.03* |
| Sexa | 1.10 (0.95, 1.26) | 0.20 | 1.07 (0.91, 1.27) | 0.39 | 1.17 (0.74, 1.87) | 0.50 |
| Influenza/ILI | 2.70 (2.03, 3.60) | <0.001* | 1.89 (1.33, 2.68) | <0.001* | 2.68 (1.07, 6.73) | 0.04* |
| Asthma | 1.33 (0.85, 2.07) | 0.21 | 1.89 (1.19, 2.99) | 0.01* | 0.54 (0.07, 4.13) | 0.55 |
| COPD | 1.52 (0.91, 2.55) | 0.11 | 1.57 (0.88, 2.77) | 0.12 | 0.80 (0.10, 6.22) | 0.83 |
| Blood disorder | 1.20 (0.73, 1.96) | 0.47 | 1.21 (0.70, 2.08) | 0.50 | 2.32 (0.71, 7.55) | 0.16 |
| Heart disease | 1.18 (0.78, 1.78) | 0.44 | 1.77 (1.16, 2.68) | 0.01* | 2.93 (1.04, 8.29) | 0.04* |
| Kidney disease | 1.12 (0.52, 2.40) | 0.77 | 2.07 (1.06, 4.03) | 0.03* | N/A | N/A |
| Liver disease | 3.38 (1.26, 9.08) | 0.02* | 3.27 (1.09, 9.79) | 0.03* | N/A | N/A |
| Neurological disease | 1.95 (1.00, 3.83) | 0.05* | 3.58 (1.96, 6.56) | <0.001* | 2.14 (0.27, 16.75) | 0.47 |
| Cancer | 1.53 (0.84, 2.77) | 0.16 | 1.27 (0.62, 2.58) | 0.51 | 2.39 (0.52, 10.94) | 0.26 |
| Significant trouble with memory | 2.33 (1.08, 5.02) | 0.03* | 4.28 (2.13, 8.58) | <0.001* | 10.43 (2.82, 38.63) | <0.001* |
This table shows the associations of patient demographics and comorbidities with declines in frailty and function at the end of the influenza season
*p ≤ 0.05, logistic regression models
aData from the respondents who identified themselves as transgender were not included in the model due to the low sample size (n = 2)
bHIV was dropped from the model due to collinearity
cKidney disease and liver disease were dropped from the model due to collinearity