Table 1.

Equations governing the voltage dependence and kinetics of currents in the model

Current general equations (except for ISK): I(V,t) = gmax × ma(V,t) × hb(V,t) × (V − Erev)
$m_{\infty }\left(V\right)=\frac{1}{\left(1+\exp \left[\left(\frac{-\left(V-V_m\right)}{k_m}\right)\right]\right)}$	$h_{\infty }\left(V\right)=\frac{1}{\left(1+\exp \left[\left(\frac{-\left(V-V_h\right)}{k_h}\right)\right]\right)}$
dm(V,t)/dt = $\frac{\left[m_{\infty }\left(V\right)-m\left(V,t\right)\right]}{{\tau }_m}$	dh(V,t)/dt = $\frac{\left[h_{\infty }\left(V\right)-h\left(V,t\right)\right]}{{\tau }_h}$	dt = 10 μs

Current	Vm (mV)	km (mV)	a	Vh (mV)	kh (mV)	b	Erev (mV)	Specific equations (τm and τh are expressed in ms)	gmax (pS/μm2)
									Soma	ABD	nABD	aD	Ax-st	AIS	Axon
INa	−28	8	3	−50	−10	1	60	τm = 0.01 + (0.33/(1 + ((V + 20)/30)2)) τh = 0.7 + (16/(1 + ((V + 50)/8)2))	25–200	25–200	25–200	25–200	25–200	1000–8000	400
IKDR	−30	9	4	—	—	0	−90	τm = (4 × exp(− (0.000729) × ((V + 32)2))) + 4	50–400	50–400	50–400	50–400	50–400	1000–8000	400
IA (soma)	−30	7	1	−75	−7	1	−90	τm = 1.029 + (4.83/(1 + exp((V + 57)/6.22)))	150	0	0	0	0	0	0
IA (dendrite)	−30	7	1	−85	−7	1	−90	τh = 25 + (120 + (78.4/(1 + exp(V + 68.5)/5.95)) − 25)/(1 + exp(( − V + 90) × 5))	0	100	100	100	100	0	0
IH	−92	−7,25	1	—	—	0	−40	τm = 556 + 1100 × exp(− 0.5 × ((V)/11.06)2)	3	3	3	3	3	0	0
ICaL	−31	7	1	—	—	0	120	τm = 1/(( − 0.209 × (V + 39.26)/(exp(− (V + 39.26)/4.111) − 1) + (0.944 × exp(− (V + 15.38)/224.1))))	1	1	1	1	1	0	0
ISK	—	—	—	—	—	—	−90	I(V,Cai) = gmax × O∞(Cai) × (V − Erev)	0.1	0.1	0.1	0.1	0.1	0	0
Calcium buffering and pump (Desthexe et al., 1993)								O∞(V) = (Cai)4/((Cai)4 + (0.00019)4)