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Two-reward operant conditioning task for concurrent alcohol and saccharin seeking. A, Timeline for ethanol and saccharin self-administration (SA), progressive ratio (PR), extinction training (EXT), and counterbalanced cue-induced reinstatement (RE) of alcohol (EtOH) and saccharin (Sac) seeking. B, C, Quantification of lever presses during baseline (BL) self-administration, EXT, and RE. D, PR test. *p < 0.05, **p < 0.01, ***p < 0.001. n = 13. For detailed statistics, see Table 1.
