Table 1.
Lever | Repeated-measures ANOVA |
Newman–Keuls post hoc test |
t test (comparison active/inactive) |
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Within-group comparison |
Between reward comparison |
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Test | df | Effect | F | p | Reward | Test | p | Test | p | Test | p | |
Active | BL, EXT | 1,24 | reward | 0.136 | 0.716 | EtOH | ||||||
Test-session | 53.099 | 0.0001 | EtOH | BL, EXT | 0.0002 | BL | 0.559 | BL | 0.0002 | |||
interaction | 0.214 | 0.648 | Sac | BL, EXT | 0.0002 | EXT | 0.939 | EXT | 0.273 | |||
EXT, RE | 1,24 | reward | 4.194 | 0.052 | ||||||||
Test-session | 61.623 | 0.0001 | EtOH | EXT, RE | 0.0001 | RE | 0.0001 | |||||
interaction | 3.851 | 0.061 | Sac | EXT, RE | 0.001 | RE | 0.007 | |||||
Inactive | BL, EXT | 1,24 | reward | 3.242 | 0.084 | Saccharin | ||||||
Test-session | 51.616 | 0.0001 | EtOH | BL, EXT | 0.0001 | BL | 0.01 | BL | 0.0012 | |||
interaction | 3.873 | 0.06 | Sac | BL, EXT | 0.001 | EXT | 0.72 | EXT | 0.273 | |||
EXT, RE | 1,24 | reward | 1.544 | 0.225 | ||||||||
Test-session | 43.587 | 0.0001 | EtOH | EXT, RE | 0.002 | RE | 0.0012 | |||||
interaction | 1.419 | 0.245 | Sac | EXT, RE | 0.0001 | RE | 0.1 |
aComparison between active and inactive lever was done using two-tailed paired t test. BL, Self-administration baseline; EXT, extinction; RE, cue-induced reinstatement; EtOH, ethanol; Sac, saccharin.