Table 3.
Lever | Repeated-measures ANOVA |
Newman–Keuls post hoc test |
t test (comparison active/inactive) |
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Within-group comparison |
Between-group comparison |
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Test | df | Effect | F | p | Reward | Test | p | Test | p | Test | p | |
Active | BL, EXT | 1,46 | reward | 1.547 | 0.219 | EtOH | ||||||
Test-session | 146.81 | 0.0001 | EtOH | BL, EXT | 0.0001 | BL | 0.07 | BL | 0.0001 | |||
interaction | 1.771 | 0.189 | Sac | BL, EXT | 0.0001 | EXT | 0.99 | EXT | 0.949 | |||
EXT, RE 1 + 2 | 1,46 | reward | 5.551 | 0.023 | ||||||||
Test-session | 176.80 | 0.0001 | EtOH | EXT, RE1 + 2 | 0.0002 | RE1 + 2 | 0.0001 | |||||
interaction | 6.788 | 0.012 | Sac | EXT, RE1 + 2 | 0.0001 | RE | 0.0009 | |||||
Inactive | BL, EXT | 1,46 | reward | 0.219 | 0.642 | Saccharin | ||||||
Test-session | 16.127 | 0.0002 | EtOH | BL, EXT | 0.006 | BL | 0.48 | BL | 0.0001 | |||
interaction | 0.336 | 0.565 | Sac | BL, EXT | 0.049 | EXT | 0.95 | EXT | 0.949 | |||
EXT, RE 1 + 2 | 1,46 | reward | 0.394 | 0.533 | ||||||||
Test-session | 7.285 | 0.009 | EtOH | EXT, RE1 + 2 | 0.195 | RE1 + 2 | 0.0001 | |||||
interaction | 0.707 | 0.405 | Sac | EXT, RE1 + 2 | 0.073 | RE | 0.31 |
aComparison between active and inactive lever was done using two-tailed paired t test. BL, Self-administration baseline; EXT, extinction; RE, cue-induced reinstatement; EtOH, ethanol; Sac, saccharin.