Figure 1.

Glutathione S-transferase-specific activity in liver and brain tissues in the rat during postnatal development. The specific activity of GST was measured using MCB as a substrate in liver (A) and brain tissue (B) homogenates prepared from P2, P7, P35, and adult (Ad) animals. Data are the mean ± SEM; n = 4–8. ***p < 0.01, statistically different from cerebral cortex activity at matching developmental stage, one-way ANOVA followed by post hoc Tukey-Kramer test. ^§p < 0.05 and ^§§§p < 0.001, significantly different from the activity measured in choroid plexus of the fourth ventricle, two-tailed paired Student's t test. CP(VL) and CP(4V), CP of the lateral and fourth ventricle, respectively; Cx, cortex.