Table 5.

Model2: Time × CI within OA during the acquisition phase

Brain region	Peak activation coordinates (x, y, z)			Z value	p value
OA-blocked (DAY1>DAY3) > OA-random (DAY1>DAY3)
R SMA, also R S1 and R M1	10	−12	58	5.79	<0.001
L CER lobe VI; also L CER lobe V, L CER lobes I–IV, and R CER vermis VIIIa	−28	−48	−30	5.36	<0.001
L S1, also L M1	−52	−30	60	5.58	<0.001
L PMv; also L central opercular cortex, L posterior STG, L temporo-occipital MTG, and inferior LOC	−62	0	30	5.15	<0.001
R CER lobe V, also R CER lobes I–IV	18	−42	−16	4.51	0.001
R insula; also R central opercular cortex, R PMv, and R planum polare	40	4	0	4.29	0.002
L planum polare, also L central opercular cortex and L temporal pole	−50	−2	−4	5.13	0.003
OA-random (DAY1>DAY3) > OA-blocked (DAY1>DAY3)
L ventral precuneus; also L/R angular gyrus, L hippocampus, and L PCC	−4	−38	50	5.95	<0.001
L SFG, also L frontal pole and L IFG	−26	30	52	4.64	<0.001
L/R medial PFC, also L SFG	0	52	20	5.18	<0.001
R CER CRII, also R occipital fusiform gyrus	24	−78	−40	4.54	<0.001
L anterior MTG; also posterior temporal fusiform cortex, L frontal orbital cortex, L temporal pole, L amygdala, and L hippocampus	−46	0	−28	4.53	<0.001
R pallidum; also R putamen, R hippocampus, and R amygdala	28	−16	−2	5.37	0.001
R temporal pole;, also R anterior STG, R anterior ITG, R anterior temporal fusiform cortex, and R anterior MTG	34	10	−32	4.84	0.004
R occipital cortex V1, also L occipital cortex V1 and V2	6	−92	0	3.98	0.004
L caudate, also L/R thalamus	−12	2	24	4.11	0.005

Shown are locations of main cluster activation peaks (MNI coordinates) and Z scores for brain regions showing a significant Time × CI interaction effect from DAY1 to DAY3 acquisition phase in OA (Z > 2.3; cluster significance: p < 0.05, corrected). R, Right; L, left; CER, cerebellum; PMv, ventral premotor cortex; STG, superior temporal gyrus; SFG, superior frontal gyrus; IFG, inferior frontal gyrus; V1, primary visual area; V2, secondary visual area.