Figure 1.

Fiber photometry of BLA neurons during fear learning. a, AAV-CaMKIIα-gCaMP6f was applied to BLA. AAV expression across all animals, with each rat represented at 10% opacity. Black circles represent the ventral tip of the fiber optic cannulae. b, Rats received differential fear conditioning (CS⁻ shock, CS⁺; CS⁻ no shock, CS⁻) and learned to fear CS⁺ but not CS⁻. c, Ca²⁺ transients during shock US delivery on CS⁺ trials and omission on CS⁻ trials on days 1 and 3 of conditioning. n indicates number of trials. d, Areas under the ΔF/F curve for the 5 s from onset of shock or shock omission across conditioning. n indicates number of trials. n = 6. *p < .05.