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Continuous versus burst kisspeptin activation of GnRH neurons. A, B, Example traces and corresponding rate meters (10 s bins) showing a GnRH neuron response to 600 pulses delivered at 10 Hz either in bursts (A) or continuously (B). C, The time course of averaged responses to burst (white circles) and continuous (gray circles) beginning at the blue arrow are shown for 7 GnRH neurons. D, The mean change in firing evoked by the two stimulation patterns is not significantly different.
