Table 2.
Constitutive expression of GFL-signaling molecules
| Number of animals | Number of retrograde-labeled bone afferent neurons | % | |
|---|---|---|---|
| Percentage of bone afferent neurons that are | |||
| GFRα1+ | 3 | 99 | 19 ± 1.9 |
| GFRα2+ | 3 | 90 | 20 ± 3.2 |
| GFRα3+ | 3 | 142 | 40 ± 2.9 |
| Proportion of GFRα1 + bone afferent neurons that express CGRP | 3 | 99 | 13 ± 12.5 |
| Proportion of GFRα2 + bone afferent neurons that express CGRP | 3 | 101 | 37 ± 7.2 |
| Proportion of GFRα3 + bone afferent neurons that express CGRP | 3 | 118 | 80 ± 7.3 |
| Proportion of GFRα1 + bone afferent neurons that express TRPV1 | 3 | 73 | 0 |
| Proportion of GFRα2 + bone afferent neurons that express TRPV1 | 3 | 90 | 14 ± 9.8 |
| Proportion of GFRα3 + bone afferent neurons that express TRPV1 | 3 | 142 | 39 ± 4.4 |
| Proportion of GFRα1 + bone afferent neurons that express TrkA | 3 | 246 | 27 ± 10.6 |
| Proportion of GFRα2 + bone afferent neurons that express TrkA | 3 | 236 | 19 ± 2.3 |
| Proportion of GFRα3 + bone afferent neurons that express TrkA | 3 | 142 | 80 ± 4.9 |
Values are given as the mean ± SEM, unless otherwise indicated.