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. 2018 Sep 12;38(37):8060–8070. doi: 10.1523/JNEUROSCI.0444-18.2018

Figure 5.

Figure 5.

Synaptic tagging in the ACC requires new protein synthesis. A, Schematic diagram of the recording procedure for this experiment. We applied the weak TBS protocol to the S2 site at 30 min after strong TBS of the S1 site in the presence of anisomycin (25 μm). B, Pooled data of the fEPSP slope from all channels for both S1-strong and S2-weak inputs. Neither strong nor weak TBS can induce L-LTP (n = 5 slices/5 mice). Anisomycin blocked the occurrence of synaptic tagging in the ACC. Large arrow indicates starting point of strong TBS application; small arrow marks the time point of weak TBS delivery. Error bars in B represent SEM.