Restoration of the aged-like neurogenic phenotype of Snca mutants by l-DOPA. a, l-DOPA experimental design. b, Striatal content of dopamine in Snca+/+ and Snca−/− mice treated with saline or l-DOPA relative to the control situation. c, Proportion of Ki67+ among GFAP+ cells in Snca+/+ and Snca−/− mice treated with saline or l-DOPA. d, Number of subependymal BrdU-LRCs in Snca+/+ and Snca−/− mice treated with saline or l-DOPA. e, Density of BrdU+NeuN+ newly generated neurons in the OB glomerular layer in Snca+/+ and Snca−/− mice treated with saline or l-DOPA. f, Olfactory habituation-dishabituation test in Snca+/+ and Snca−/− mice treated with l-DOPA. *p < 0.05 (two-way ANOVA). **p < 0.01 (two-way ANOVA). ***p < 0.001 (two-way ANOVA).