Figure 2.

Selective expression of Tmem98 in differentiated oligodendrocytes. A–I, Spinal cord sections from P7 wild-type mice were subject to Tmem98 ISH, followed by immunohistochemical staining with anti-SOX10 (A, B), anti-CC1 (C, D), anti-MYRF (E, F), or anti-PDGFRA (G–I). B, D, and F are higher magnifications of the outlined areas in A, C, and E, respectively. J–M, Tmem98 expression in Nkx2.2-CKO (J, K) and Myrf-CKO (L, M) mutant spinal cords is dramatically reduced at P3 stages. Scale bars, 100 μm.