Inhibition of MYRF self-cleavage by TMEM98. A, The self-cleavage of MYRF was suppressed when TMEM98 was coexpressed. B, The nuclear translocation of MYRF N-fragments released from full-length proteins was blocked when TMEM98 was coexpressed. C, TMEM98 does not interfere with the nuclear translocation of N-fragments of MYRF (1–588). Scale bars, 20 μm. WB, Western blot.