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. Author manuscript; available in PMC: 2019 Jun 27.
Published in final edited form as: Anal Chem. 2019 Mar 15;91(9):5794–5801. doi: 10.1021/acs.analchem.9b00024

Figure 4.

Figure 4.

Quantitative phosphoproteome analysis of human islet samples. (a) PCA readily separates human islet samples by cytokine treatment but not by the respective TMT set. (b) Unsupervised hierarchical cluster analysis of phosphoproteome of the human islet samples. (c) The enriched Reactome signaling pathways (top 15) for up-regulated phosphorylation sites after cytokine treatment. (d) Distribution of the abundance of phosphorylation sites of STAT1 (S727) in human islet samples before and after cytokine treatment.