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. 2019 Jun 21;14:4461–4474. doi: 10.2147/IJN.S205276

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© 2019 Mao et al.

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Cryo-EM micrographs of VCR liposome formulations. (A–C) SM/Chol/mPEG-DSPE (79/20/1, w/w) liposomes using a TEA-SOS gradient for VCR loading at different drug/lipid ratios of 1/10 (A), 1/5 (B) and 1/2 (C). (D) SM/Chol (73.5:29.5, w/w) liposome using a pH gradient for VCR loading.