Table 1.
List of IL-1 family cytokines with their respective nomenclatures, Uniprot IDs, alternative names, domains, and structures by PDB code.
| Cytokines | Uniprot | Alternative name | Main Domain | Structure | Structure | Structure | Structure | Structure |
|---|---|---|---|---|---|---|---|---|
| IL1-F1 | P01583 | IL-1α | 113-271 | 2ILA (Cα only) | 2KKI (NMR) | |||
| IL1-F2 | P01584 | IL-1β | 117-269 | 2I1B | 6I1B(NMR) | 1ITB (with IL-1RI) | 4DEP (with IL-1RI/IL-1RAcP) | 3O4O (with IL-1RII/ IL1-RAcP) |
| IL1-F3 | P18510 | Il-1Ra, anakinra | 26-177 | 1ILR | 1IRP (NMR) | |||
| IL1-F4 | Q14116 | IL-18 | 37-193 | 2VXT (with antibody) | 1J0S (NMR) | 3F62 (with IL-18BP) | 3WO4 (IL-18R/IL-18RAcP/IL-18) | 3WO3 (IL-18R/IL-18RAcP/IL-18) |
| IL-1F5 | Q9UBH0 | IL-36Ra | 1-155 | 1MD6 (murine) | 4P0J (chimera) | 4P0K (chimera) | 4P0L (chimera) | |
| IL-1F6 | Q9UHA7 | IL-36α | 1-158 | |||||
| IL-1F7 | Q9NZH6 | IL-37 | 46-218 | 5HN1 | ||||
| IL-1F8 | Q9NZH7 | IL-36β, IL1-H2 | 1-157 | |||||
| IL-1F9 | Q9NZH8 | IL-36γ | 1-169 | 4IZE | ||||
| IL1-F10 | Q8WWZ1 | IL-38 | 1-152 | 5BOW | ||||
| IL-1F11 | O95760 | IL-33, NF-HEV | 112-270 | 2KLL (NMR) | 4KC3 (ST2/IL-33) |