Table 2. Central composite design (CCD) of factors in coded value for optimization of the antifungal activity yield.
| Run No. | Natural Values of Parameters | Coded Values of Parameters |
Observed Antifungal Activity
y (mm) |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| X1 (g l-1) | X2 (g l-1) | X3 (g l-) | X4 | x0 | x1 | x2 | x3 | x4 | ||
| 1 | 6 | 3 | 1.25 | 5 | 1 | -1 | -1 | -1 | -1 | 13.95 |
| 2 | 14 | 3 | 1.25 | 5 | 1 | 1 | -1 | -1 | -1 | 17.64 |
| 3 | 6 | 5 | 1.25 | 5 | 1 | -1 | 1 | -1 | -1 | 0 |
| 4 | 14 | 5 | 1.25 | 5 | 1 | 1 | 1 | -1 | -1 | 17.53 |
| 5 | 6 | 3 | 2.75 | 5 | 1 | -1 | -1 | 1 | -1 | 19.55 |
| 6 | 14 | 3 | 2.75 | 5 | 1 | 1 | -1 | 1 | -1 | 12.06 |
| 7 | 6 | 5 | 2.75 | 5 | 1 | -1 | 1 | 1 | -1 | 0 |
| 8 | 14 | 5 | 2.75 | 5 | 1 | 1 | 1 | 1 | -1 | 16.83 |
| 9 | 6 | 3 | 1.25 | 9 | 1 | -1 | -1 | -1 | 1 | 12.56 |
| 10 | 14 | 3 | 1.25 | 9 | 1 | 1 | -1 | -1 | 1 | 9.02 |
| 11 | 6 | 5 | 1.25 | 9 | 1 | -1 | 1 | -1 | 1 | 25.42 |
| 12 | 14 | 5 | 1.25 | 9 | 1 | 1 | 1 | -1 | 1 | 0 |
| 13 | 6 | 3 | 2.75 | 9 | 1 | -1 | -1 | 1 | 1 | 20.88 |
| 14 | 14 | 3 | 2.75 | 9 | 1 | 1 | -1 | 1 | 1 | 14.45 |
| 15 | 6 | 5 | 2.75 | 9 | 1 | -1 | 1 | 1 | 1 | 18.16 |
| 16 | 14 | 5 | 2.75 | 9 | 1 | 1 | 1 | 1 | 1 | 9.23 |
| 17 | 10 | 4 | 2 | 7 | 1 | 0 | 0 | 0 | 0 | 13.10 |
| 18 | 10 | 4 | 2 | 7 | 1 | 0 | 0 | 0 | 0 | 13.50 |
| 19 | 10 | 4 | 2 | 7 | 1 | 0 | 0 | 0 | 0 | 13.18 |
| 20 | 10 | 4 | 2 | 7 | 1 | 0 | 0 | 0 | 0 | 13.00 |
| 21 | 10 | 4 | 2 | 7 | 1 | 0 | 0 | 0 | 0 | 13.68 |
| 22 | 10 | 4 | 2 | 7 | 1 | 0 | 0 | 0 | 0 | 13.7 |
| 23 | 2 | 4 | 2 | 7 | 1 | -2 | 0 | 0 | 0 | 14.02 |
| 24 | 18 | 4 | 2 | 7 | 1 | 2 | 0 | 0 | 0 | 10.66 |
| 25 | 10 | 2 | 2 | 7 | 1 | 0 | -2 | 0 | 0 | 15.50 |
| 26 | 10 | 6 | 2 | 7 | 1 | 0 | 2 | 0 | 0 | 12.92 |
| 27 | 10 | 4 | 0.5 | 7 | 1 | 0 | 0 | -2 | 0 | 9.3 |
| 28 | 10 | 4 | 3.5 | 7 | 1 | 0 | 0 | 2 | 0 | 14.6 |
| 29 | 10 | 4 | 2 | 3 | 1 | 0 | 0 | 0 | -2 | 0 |
| 30 | 10 | 4 | 2 | 11 | 1 | 0 | 0 | 0 | 2 | 17.80 |